Assay Detail
Functional
CHEMBL2077575
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of PGF2alpha uptake in PGT-expressing HeLa cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | HeLa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Solute carrier organic anion transporter family member 2A1 (CHEMBL2073680) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Identification and characterization of a prostaglandin transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.87 | 5.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL145704 | BROMCRESOL GREEN | — | 1 | 5.44 |
| CHEMBL453904 | SULFOBROMOPHTHALEIN SODIUM | -1.0 | 1 | 5.24 |
| CHEMBL1646 | INDOCYANINE GREEN | 4.0 | 1 | 4.46 |
| CHEMBL35 | FUROSEMIDE | 4.0 | 1 | 4.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL145704 | BROMCRESOL GREEN | Ki | = | 3600.0 | nM | 5.44 |
| CHEMBL453904 | SULFOBROMOPHTHALEIN SODIUM | Ki | = | 5800.0 | nM | 5.24 |
| CHEMBL1646 | INDOCYANINE GREEN | Ki | = | 35000.0 | nM | 4.46 |
| CHEMBL35 | FUROSEMIDE | Ki | = | 47000.0 | nM | 4.33 |