Assay Detail
Functional
CHEMBL2077582
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 25000 uM) in PEPT1-expressing CHO cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.20 | 4.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL17697 | — | — | 1 | 4.20 |
| CHEMBL174 | AMPICILLIN | 4.0 | 1 | - |
| CHEMBL54278 | GLYCYLGLYCYLGLYCINE | — | 1 | - |
| CHEMBL1727 | CEPHALEXIN ANHYDROUS | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL17697 | — | IC50 | = | 63000.0 | nM | 4.20 |
| CHEMBL174 | AMPICILLIN | IC50 | = | 10000000.0 | nM | - |
| CHEMBL54278 | GLYCYLGLYCYLGLYCINE | IC50 | = | 1400000.0 | nM | - |
| CHEMBL1727 | CEPHALEXIN ANHYDROUS | IC50 | = | 5200000.0 | nM | - |