Assay Detail
Functional
CHEMBL2077860
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of Salicylate uptake in Oat2-expressing LLC PK1 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | LLC-PK1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Solute carrier family 22 member 7 (CHEMBL2073671) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
TP-search Transporter Database
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.53 | 5.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1646 | INDOCYANINE GREEN | 4.0 | 1 | 5.94 |
| CHEMBL571 | KETOPROFEN | 4.0 | 1 | 5.74 |
| CHEMBL472 | GLYBURIDE | 4.0 | 1 | 4.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1646 | INDOCYANINE GREEN | Ki | = | 1150.0 | nM | 5.94 |
| CHEMBL571 | KETOPROFEN | Ki | = | 1840.0 | nM | 5.74 |
| CHEMBL472 | GLYBURIDE | Ki | = | 12300.0 | nM | 4.91 |