Assay Detail
Functional
CHEMBL2078640
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing Sf9 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | Sf9 |
| Subcellular | Membrane vesicle |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
ATP-binding cassette sub-family C member 4 (CHEMBL1743128) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.52 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL259898 | PRASTERONE SULFURIC ACID | -1.0 | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL259898 | PRASTERONE SULFURIC ACID | IC50 | = | 3000.0 | nM | 5.52 |