Assay Detail
Functional
CHEMBL2090145
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Antineoplastic activity against human PC3 cells after 72 hrs by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.01 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2088287 | — | — | 1 | 5.52 |
| CHEMBL2088291 | — | — | 1 | 5.40 |
| CHEMBL2088286 | — | — | 1 | 5.30 |
| CHEMBL2088285 | — | — | 1 | 5.22 |
| CHEMBL2088290 | — | — | 1 | 5.16 |
| CHEMBL6206 | BROMOENOL LACTONE | — | 1 | 4.85 |
| CHEMBL2088283 | — | — | 1 | 4.85 |
| CHEMBL2088284 | — | — | 1 | 4.80 |
| CHEMBL2088288 | — | — | 1 | 4.60 |
| CHEMBL2088289 | — | — | 1 | 4.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2088287 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL2088291 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL2088286 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL2088285 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL2088290 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL6206 | BROMOENOL LACTONE | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL2088283 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL2088284 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL2088288 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL2088289 | — | IC50 | = | 39000.0 | nM | 4.41 |