Assay Detail
Functional
CHEMBL2090366
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human P2Y6 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.44 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2086770 | — | — | 1 | 7.55 |
| CHEMBL130266 | URIDINE_DIPHOSPHATE | — | 1 | 7.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2086770 | — | EC50 | = | 28.0 | nM | 7.55 |
| CHEMBL130266 | URIDINE_DIPHOSPHATE | EC50 | = | 47.0 | nM | 7.33 |