Assay Detail
Functional
CHEMBL2090614
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplasmodial against chloroquine-rsistant Plasmodium falciparum W2 after 2 days by flow cytometry
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.41 | 7.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL170 | QUININE | 4.0 | 1 | 7.73 |
| CHEMBL2088682 | — | — | 1 | 5.08 |
| CHEMBL2088678 | — | — | 1 | - |
| CHEMBL2088679 | — | — | 1 | - |
| CHEMBL2088680 | — | — | 1 | - |
| CHEMBL2088681 | — | — | 1 | - |
| CHEMBL2088683 | — | — | 1 | - |
| CHEMBL2088684 | — | — | 1 | - |
| CHEMBL2088685 | — | — | 1 | - |
| CHEMBL2088686 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL170 | QUININE | IC50 | = | 18.7 | nM | 7.73 |
| CHEMBL2088682 | — | IC50 | = | 8393.0 | nM | 5.08 |
| CHEMBL2088678 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2088679 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2088680 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2088681 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2088683 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2088684 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2088685 | — | IC50 | - | — | - | |
| CHEMBL2088686 | — | IC50 | - | — | - |