Assay Detail
Functional
CHEMBL2090753
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Antimalarial activity against liver stages of Plasmodium falciparum after 96 hrs
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting the liver stage of malaria parasites: a yet unmet goal.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.51 | 5.54 |
| INH | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL11301 | DESFERRITHIOCIN | — | 1 | 5.54 |
| CHEMBL556 | DEFEROXAMINE | 4.0 | 1 | 5.47 |
| CHEMBL1738 | DEXRAZOXANE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL11301 | DESFERRITHIOCIN | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL556 | DEFEROXAMINE | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL1738 | DEXRAZOXANE | INH | = | 50.0 | uM | - |