Assay Detail
Functional
CHEMBL2091785
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Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A novel thiazolidine compound induces caspase-9 dependent apoptosis in cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.40 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 5.46 |
| CHEMBL2087602 | — | — | 1 | 5.33 |
| CHEMBL65 | CAMPTOTHECIN | -1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL2087602 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL65 | CAMPTOTHECIN | IC50 | < | 1000.0 | nM | - |