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Assay Detail

CHEMBL2092477

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of RET
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Proto-oncogene tyrosine-protein kinase receptor Ret (CHEMBL2041)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Novel triazolopyridylbenzamides as potent and selective p38α inhibitors.
Aiguadé J, Balagué C, Carranco I, Caturla F, Domínguez M, Eastwood P, Esteve C, González J, Lumeras W, Orellana A, Preciado S, Roca R, Vidal L, Vidal B.
Bioorg Med Chem Lett (2012) 22 : 3431 -3436
PubMed 22521646 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2087742 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2087742 IC50 = 2000.0 nM 5.70