Assay Detail
Binding
CHEMBL2092541
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Displacement of [125I]IMPY from amyloid beta (1 to 42) after 2 hrs by gamma counting
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
¹⁸F-labeled 2-phenylquinoxaline derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.27 | 8.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1774461 | FLORBETAPIR F 18 | 4.0 | 1 | 8.54 |
| CHEMBL2086409 | — | — | 1 | 8.28 |
| CHEMBL2087932 | — | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1774461 | FLORBETAPIR F 18 | Ki | = | 2.9 | nM | 8.54 |
| CHEMBL2086409 | — | Ki | = | 5.3 | nM | 8.28 |
| CHEMBL2087932 | — | Ki | = | 10.0 | nM | 8.00 |