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Assay Detail

CHEMBL2148716

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human MCHR1 expressed in COS7 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type COS-7
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Melanin-concentrating hormone receptor 1 (CHEMBL344)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

[¹⁸F]FE@SNAP-A new PET tracer for the melanin concentrating hormone receptor 1 (MCHR1): microfluidic and vessel-based approaches.
Philippe C, Ungersboeck J, Schirmer E, Zdravkovic M, Nics L, Zeilinger M, Shanab K, Lanzenberger R, Karanikas G, Spreitzer H, Viernstein H, Mitterhauser M, Wadsak W.
Bioorg Med Chem (2012) 20 : 5936 -5940
PubMed 22921745 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.74 9.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2146615 1 9.74

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2146615 Kd = 0.18 nM 9.74