Assay Detail
Binding
CHEMBL2154366
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Binding affinity to T-type calcium channel
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Short-acting T-type calcium channel antagonists significantly modify sleep architecture in rodents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 9.10 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2151145 | — | — | 1 | 9.70 |
| CHEMBL2151144 | — | — | 1 | 9.52 |
| CHEMBL1684954 | — | — | 1 | 8.92 |
| CHEMBL2151147 | — | — | 1 | 8.26 |
| CHEMBL2151146 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2151145 | — | Ki | = | 0.2 | nM | 9.70 |
| CHEMBL2151144 | — | Ki | = | 0.3 | nM | 9.52 |
| CHEMBL1684954 | — | Ki | = | 1.2 | nM | 8.92 |
| CHEMBL2151147 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL2151146 | — | Ki | - | — | - |