Assay Detail
Functional
CHEMBL2154389
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at Cav3.3 at -80 mV holding potential by whole cell patch clamp analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Voltage-dependent T-type calcium channel subunit alpha-1I (CHEMBL5558) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Short-acting T-type calcium channel antagonists significantly modify sleep architecture in rodents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.58 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2151147 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2151147 | — | IC50 | = | 264.0 | nM | 6.58 |