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Assay Detail

CHEMBL2155172

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Non-competitive inhibition of Spanish V-line rabbit liver alpha-amylase using starch as substrate by Dixon plot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibition of α-glucosidase and α-amylase by diaryl derivatives of imidazole-thione and 1,2,4-triazole-thiol.
Balba M, El-Hady NA, Taha N, Rezki N, El Ashry el SH.
Eur J Med Chem (2011) 46 : 2596 -2601
PubMed 21497424 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 4.21 4.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2153286 1 4.22
CHEMBL2153287 1 4.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2153286 Ki = 60000.0 nM 4.22
CHEMBL2153287 Ki = 65000.0 nM 4.19