Assay Detail
Functional
CHEMBL2156197
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Cytotoxicity against human HT-29 cells after 96 hrs by SRB assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antitumor activity of ring A modified glycyrrhetinic acid derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.61 | 4.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2151732 | — | — | 1 | 4.61 |
| CHEMBL493512 | — | — | 1 | - |
| CHEMBL590534 | — | — | 1 | - |
| CHEMBL2151730 | — | — | 1 | - |
| CHEMBL2151731 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2151732 | — | IC50 | = | 24720.0 | nM | 4.61 |
| CHEMBL493512 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL590534 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2151730 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2151731 | — | IC50 | > | 30000.0 | nM | - |