Assay Detail
Binding
CHEMBL2156473
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]echistatin from integrin alpha5beta3 after 3 hrs by gamma counter
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Camptothecins in tumor homing via an RGD sequence mimetic.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 8.27 | 10.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2153647 | — | — | 1 | 10.09 |
| CHEMBL2153643 | — | — | 1 | 8.89 |
| CHEMBL2153642 | — | — | 1 | 8.64 |
| CHEMBL2153644 | — | — | 1 | 8.64 |
| CHEMBL312929 | — | — | 1 | 8.49 |
| CHEMBL2153645 | — | — | 1 | 8.32 |
| CHEMBL2153646 | — | — | 1 | 8.30 |
| CHEMBL2153641 | — | — | 1 | 6.96 |
| CHEMBL2153640 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2153647 | — | IC50 | = | 0.082 | nM | 10.09 |
| CHEMBL2153643 | — | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL2153642 | — | IC50 | = | 2.3 | nM | 8.64 |
| CHEMBL2153644 | — | IC50 | = | 2.28 | nM | 8.64 |
| CHEMBL312929 | — | IC50 | = | 3.26 | nM | 8.49 |
| CHEMBL2153645 | — | IC50 | = | 4.83 | nM | 8.32 |
| CHEMBL2153646 | — | IC50 | = | 4.97 | nM | 8.30 |
| CHEMBL2153641 | — | IC50 | = | 108.9 | nM | 6.96 |
| CHEMBL2153640 | — | IC50 | = | 800.0 | nM | 6.10 |