Assay Detail
Binding
CHEMBL2157355
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Inhibition of Bacillus stearothermophilus alpha-glucosidase type 4
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Geobacillus stearothermophilus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Dibenzocycloheptanoids from the leaves of Cinnamomum subavenium.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 4.82 | 7.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL404271 | ACARBOSE | 4.0 | 1 | 7.47 |
| CHEMBL2152484 | SUBAVENOSIDE E | — | 1 | 4.72 |
| CHEMBL2152490 | — | — | 1 | 4.55 |
| CHEMBL2152489 | — | — | 1 | 4.40 |
| CHEMBL2152483 | SUBAVENOSIDE D | — | 1 | 4.29 |
| CHEMBL245067 | PHLORIZIN | — | 1 | 4.22 |
| CHEMBL2152485 | — | — | 1 | 4.11 |
| CHEMBL2152481 | — | — | 1 | - |
| CHEMBL2152482 | SUBAVENOSIDE A | — | 1 | - |
| CHEMBL2152486 | — | — | 1 | - |
| CHEMBL2152487 | — | — | 1 | - |
| CHEMBL2152488 | — | — | 1 | - |
| CHEMBL1950045 | HYDROXYTYROSOL | 3.0 | 1 | - |
| CHEMBL498879 | NICOTIFLOROSIDE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL404271 | ACARBOSE | IC50 | = | 34.0 | nM | 7.47 |
| CHEMBL2152484 | SUBAVENOSIDE E | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL2152490 | — | IC50 | = | 28300.0 | nM | 4.55 |
| CHEMBL2152489 | — | IC50 | = | 39800.0 | nM | 4.40 |
| CHEMBL2152483 | SUBAVENOSIDE D | IC50 | = | 50700.0 | nM | 4.29 |
| CHEMBL245067 | PHLORIZIN | IC50 | = | 60500.0 | nM | 4.22 |
| CHEMBL2152485 | — | IC50 | = | 77100.0 | nM | 4.11 |
| CHEMBL2152481 | — | IC50 | = | 117700.0 | nM | - |
| CHEMBL2152482 | SUBAVENOSIDE A | IC50 | = | 141600.0 | nM | - |
| CHEMBL2152486 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL2152487 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL2152488 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL1950045 | HYDROXYTYROSOL | IC50 | = | 109300.0 | nM | - |
| CHEMBL498879 | NICOTIFLOROSIDE | IC50 | = | 109900.0 | nM | - |