Assay Detail
Functional
CHEMBL2157693
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at 5HT3 receptor expressed in N1E115 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | N1E115 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery and development of α7 nicotinic acetylcholine receptor modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.49 | 7.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2151439 | FACINICLINE | 2.0 | 1 | 7.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2151439 | FACINICLINE | IC50 | = | 32.7 | nM | 7.49 |