Assay Detail
Functional
CHEMBL2157803
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at wild type monkey alpha7 nAChR by whole cell patch clamp assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Macaca mulatta |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Neuronal acetylcholine receptor subunit alpha-7 (CHEMBL2150833) ↗| Type | SINGLE PROTEIN |
| Organism | Macaca mulatta |
Publication
Discovery and development of α7 nicotinic acetylcholine receptor modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.40 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2151439 | FACINICLINE | 2.0 | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2151439 | FACINICLINE | EC50 | = | 400.0 | nM | 6.40 |