Assay Detail
Binding
CHEMBL2160774
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GnRH receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Gonadotropin-releasing hormone receptor (CHEMBL1855) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The therapeutic journey of benzimidazoles: a review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.95 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL493185 | — | — | 1 | 8.15 |
| CHEMBL493344 | — | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL493185 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL493344 | — | IC50 | = | 18.0 | nM | 7.75 |