Assay Detail
Binding
CHEMBL2167045
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Displacement of [125I]-IABN from D2 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A straightforward approach for engineering efficacy and selectivity at GPCRs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.21 | 7.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL125916 | — | — | 1 | 7.43 |
| CHEMBL346692 | — | — | 1 | 6.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL125916 | — | Ki | = | 37.4 | nM | 7.43 |
| CHEMBL346692 | — | Ki | = | 103.0 | nM | 6.99 |