Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL2167502

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HIV1 protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 1
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Protease (CHEMBL2366517)
Type SINGLE PROTEIN
Organism Human immunodeficiency virus 1

Publication

Rational approaches to improving selectivity in drug design.
Huggins DJ, Sherman W, Tidor B.
J Med Chem (2012) 55 : 1424 -1444
PubMed 22239221 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 10.70 10.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL301728 ACETYLPEPSTATIN 1 10.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL301728 ACETYLPEPSTATIN Ki = 0.02 nM 10.70