Assay Detail
Functional
CHEMBL2168447
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Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.27 | 5.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL448434 | — | — | 1 | 5.97 |
| CHEMBL481608 | — | — | 1 | 5.57 |
| CHEMBL324162 | — | — | 1 | 5.54 |
| CHEMBL393220 | ATORVASTATIN CALCIUM | 4.0 | 1 | 5.38 |
| CHEMBL2164237 | — | — | 1 | 5.34 |
| CHEMBL479464 | — | — | 1 | 5.20 |
| CHEMBL2164235 | — | — | 1 | 5.17 |
| CHEMBL2164234 | — | — | 1 | 5.06 |
| CHEMBL112210 | — | — | 1 | 5.05 |
| CHEMBL2164236 | — | — | 1 | 5.00 |
| CHEMBL2164238 | — | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL448434 | — | IC50 | = | 1060.0 | nM | 5.97 |
| CHEMBL481608 | — | IC50 | = | 2690.0 | nM | 5.57 |
| CHEMBL324162 | — | IC50 | = | 2890.0 | nM | 5.54 |
| CHEMBL393220 | ATORVASTATIN CALCIUM | IC50 | = | 4220.0 | nM | 5.38 |
| CHEMBL2164237 | — | IC50 | = | 4530.0 | nM | 5.34 |
| CHEMBL479464 | — | IC50 | = | 6370.0 | nM | 5.20 |
| CHEMBL2164235 | — | IC50 | = | 6820.0 | nM | 5.17 |
| CHEMBL2164234 | — | IC50 | = | 8640.0 | nM | 5.06 |
| CHEMBL112210 | — | IC50 | = | 8850.0 | nM | 5.05 |
| CHEMBL2164236 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL2164238 | — | IC50 | = | 21800.0 | nM | 4.66 |