Assay Detail
Binding
CHEMBL2168785
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of dehydrogenase activity of N-terminal 6His-tagged human AKR1B10 V301L mutant expressed in Escherichia coli BL21(DE3) assessed as NADP+-linked geraniol oxidation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Aldo-keto reductase family 1 member B10 (CHEMBL5983) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.86 | 6.03 |