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Assay Detail

CHEMBL2173000

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of NGF binding to p75NTR
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Beta-nerve growth factor (CHEMBL1649058)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Chemical modulators working at pharmacological interface of target proteins.
Jeon YH, Lee JY, Kim S.
Bioorg Med Chem (2012) 20 : 1893 -1901
PubMed 22227462 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1397270 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1397270 IC50 = 1000.0 nM 6.00