Assay Detail
Binding
CHEMBL2173363
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of G9a by fluorescence polarization assay in presence of fluorescein-labeled H3 peptide
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase EHMT2 (CHEMBL6032) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Oncoepigenomics: making histone lysine methylation count.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.43 | 8.43 |
| IC50 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1231795 | — | — | 2 | 8.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1231795 | — | Ki | = | 3.7 | nM | 8.43 |
| CHEMBL1231795 | — | IC50 | < | 15.0 | nM | - |