Assay Detail
Binding
CHEMBL2173370
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SUV39H1
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase SUV39H1 (CHEMBL1795118) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Oncoepigenomics: making histone lysine methylation count.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.68 | 7.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL499593 | CHETOMIN | — | 1 | 7.18 |
| CHEMBL331627 | GLIOTOXIN | — | 1 | 6.58 |
| CHEMBL2172426 | — | — | 1 | 6.28 |
| CHEMBL1089088 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL499593 | CHETOMIN | IC50 | = | 66.0 | nM | 7.18 |
| CHEMBL331627 | GLIOTOXIN | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL2172426 | — | IC50 | = | 530.0 | nM | 6.28 |
| CHEMBL1089088 | — | IC50 | > | 10000.0 | nM | - |