Assay Detail
Functional
CHEMBL2173792
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Antifungal activity against 10'7 CFU/mL Candida albicans PC31 preincubated for 30 mins in dark followed by irradiation measured after 30 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Mechanistic aspects of the photodynamic inactivation of Candida albicans induced by cationic porphyrin derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.61 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2171698 | — | — | 1 | 6.80 |
| CHEMBL2171697 | — | — | 1 | 6.64 |
| CHEMBL65606 | TMPYP4 | — | 1 | 6.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2171698 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL2171697 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL65606 | TMPYP4 | IC50 | = | 410.0 | nM | 6.39 |