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Assay Detail

CHEMBL2174067

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of sheep COX2 pre-incubated for 5 mins before anandamide acid substrate addition by peroxidase activity detection based oxygen electrode assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Ovis aries
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prostaglandin G/H synthase 2 (CHEMBL4102)
Type SINGLE PROTEIN
Organism Ovis aries

Publication

Identification and characterization of carprofen as a multitarget fatty acid amide hydrolase/cyclooxygenase inhibitor.
Favia AD, Habrant D, Scarpelli R, Migliore M, Albani C, Bertozzi SM, Dionisi M, Tarozzo G, Piomelli D, Cavalli A, De Vivo M.
J Med Chem (2012) 55 : 8807 -8826
PubMed 23043222 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.70 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL596757 1 4.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL596757 IC50 = 20000.0 nM 4.70