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Assay Detail

CHEMBL2174820

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MCF7 cells incubated for 24 hrs measured after 5 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and biological characterization of protease-activated prodrugs of doxazolidine.
Barthel BL, Rudnicki DL, Kirby TP, Colvin SM, Burkhart DJ, Koch TH.
J Med Chem (2012) 55 : 6595 -6607
PubMed 22742660 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2172463 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2172463 IC50 = 199.53 nM 6.70