Assay Detail

CHEMBL2174830

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Functional

Growth inhibition of human SW480 cells by MTT assay

ChEMBL ↗

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Target

SW480 (CHEMBL612544) ↗

Open DB target context

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Primary target SW480

CHEMBL612544

Anchored from Assay target.

Protein identity SW480

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	SW480
Confidence	1 — Organism
Curated By	Autocuration

Target

SW480 (CHEMBL612544) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Naphthomycins L-N, ansamycin antibiotics from Streptomyces sp. CS.

Yang YH, Fu XL, Li LQ, Zeng Y, Li CY, He YN, Zhao PJ.
J Nat Prod (2012) 75 : 1409 -1413
PubMed 22742732 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.93	4.93

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2172467	NAPHTHOMYCIN A	—	1	4.93

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2172467	NAPHTHOMYCIN A	IC50	=	11660.0	nM	4.93