Assay Detail
Binding
CHEMBL2175176
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Inhibition of STAT1 SH2 domain assessed as inhibition of STAT1 SH2-phosphotyrosine interaction by AlphaScreen assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Signal transducer and activator of transcription 1-alpha/beta (CHEMBL6101) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.00 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL207155 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL207155 | — | IC50 | = | 10000.0 | nM | 5.00 |