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Assay Detail

CHEMBL2175254

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Binding
Binding affinity to vasopressin V2 receptor in rabbit kidney membranes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Tissue Kidney
Subcellular Membrane
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Selective fluorescent nonpeptidic antagonists for vasopressin V₂ GPCR: application to ligand screening and oligomerization assays.
Loison S, Cottet M, Orcel H, Adihou H, Rahmeh R, Lamarque L, Trinquet E, Kellenberger E, Hibert M, Durroux T, Mouillac B, Bonnet D.
J Med Chem (2012) 55 : 8588 -8602
PubMed 22984902 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.13 8.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL119793 1 8.14
CHEMBL603708 1 8.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL119793 Ki = 7.2 nM 8.14
CHEMBL603708 Ki = 7.6 nM 8.12