Assay Detail
Binding
CHEMBL2175260
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Binding affinity to vasopressin V2 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Selective fluorescent nonpeptidic antagonists for vasopressin V₂ GPCR: application to ligand screening and oligomerization assays.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.09 | 8.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL119793 | — | — | 1 | 8.14 |
| CHEMBL603708 | — | — | 1 | 8.12 |
| CHEMBL420762 | MOZAVAPTAN | 4.0 | 1 | 8.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL119793 | — | Ki | = | 7.2 | nM | 8.14 |
| CHEMBL603708 | — | Ki | = | 7.5 | nM | 8.12 |
| CHEMBL420762 | MOZAVAPTAN | Ki | = | 9.7 | nM | 8.01 |