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Assay Detail

CHEMBL2182980

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to mGLUR2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Metabotropic glutamate receptor 2 (CHEMBL5137)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Radiosynthesis of PET radiotracer as a prodrug for imaging group II metabotropic glutamate receptors in vivo.
Wang JQ, Zhang Z, Kuruppu D, Brownell AL.
Bioorg Med Chem Lett (2012) 22 : 1958 -1962
PubMed 22318160 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.66 8.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL186453 1 8.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL186453 Ki = 2.2 nM 8.66