Assay Detail
Functional
CHEMBL2183797
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Antiapicomplexan activity against chloroquine-sensitive Plasmodium falciparum D6 assessed as growth inhibition after 72 hrs by MSF assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Salicylanilide inhibitors of Toxoplasma gondii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.24 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 8.15 |
| CHEMBL532497 | — | — | 1 | 6.11 |
| CHEMBL536151 | IMD-0354 | 1.0 | 1 | 5.85 |
| CHEMBL2179161 | — | — | 1 | 5.57 |
| CHEMBL2179170 | — | — | 1 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL532497 | — | IC50 | = | 770.0 | nM | 6.11 |
| CHEMBL536151 | IMD-0354 | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL2179161 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL2179170 | — | IC50 | = | 3100.0 | nM | 5.51 |