Assay Detail
Binding
CHEMBL2183864
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetry
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Orotidine phosphate decarboxylase (CHEMBL5173) ↗| Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
Publication
Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.66 | 4.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2178721 | — | — | 1 | 4.66 |
| CHEMBL2178722 | — | — | 1 | - |
| CHEMBL307679 | — | — | 1 | - |
| CHEMBL214393 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2178721 | — | Ki | = | 22100.0 | nM | 4.66 |
| CHEMBL2178722 | — | Ki | > | 1000000.0 | nM | - |
| CHEMBL307679 | — | Ki | > | 10000000.0 | nM | - |
| CHEMBL214393 | — | Ki | = | 210000.0 | nM | - |