Assay Detail
Binding
CHEMBL2184195
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Binding affinity to Escherichia coli GyrB
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
ATP-binding site of bacterial enzymes as a target for antibacterial drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.24 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL303984 | CHLOROBIOCIN | — | 1 | 8.92 |
| CHEMBL36506 | NOVOBIOCIN | 4.0 | 1 | 7.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL303984 | CHLOROBIOCIN | Kd | = | 1.2 | nM | 8.92 |
| CHEMBL36506 | NOVOBIOCIN | Kd | = | 28.0 | nM | 7.55 |