Assay Detail
Binding
CHEMBL2184411
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Binding affinity to AT1 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Chemokine receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.10 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL539423 | SPARSENTAN | 4.0 | 1 | 9.10 |
| CHEMBL1513 | IRBESARTAN | 4.0 | 1 | 9.10 |
| CHEMBL24461 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL539423 | SPARSENTAN | Ki | = | 0.8 | nM | 9.10 |
| CHEMBL1513 | IRBESARTAN | Ki | = | 0.8 | nM | 9.10 |
| CHEMBL24461 | — | Ki | > | 10000.0 | nM | - |