Assay Detail
Functional
CHEMBL2184872
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Antagonist activity at CCR1 assessed as inhibition of CCL3-induced chemotaxis by cell based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Chemokine receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.25 | 8.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2178569 | — | — | 1 | 8.47 |
| CHEMBL486030 | — | — | 1 | 8.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2178569 | — | IC50 | = | 3.4 | nM | 8.47 |
| CHEMBL486030 | — | IC50 | = | 9.6 | nM | 8.02 |