Assay Detail

CHEMBL2184875

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Binding affinity to mouse CCR1 by radioligand binding assay

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

C-C chemokine receptor type 1 (CHEMBL3872) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

C-C chemokine receptor type 1 (CHEMBL3872) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target C-C chemokine receptor type 1

CHEMBL3872

Anchored from Assay target.

Protein identity C-C chemokine receptor type 1

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Mus musculus
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

C-C chemokine receptor type 1 (CHEMBL3872) ↗

Type	SINGLE PROTEIN
Organism	Mus musculus

Publication

Chemokine receptor antagonists.

Pease J, Horuk R.
J Med Chem (2012) 55 : 9363 -9392
PubMed 22931505 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Kd	1	6.70	6.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL232656	BX 471 FREE BASE	2.0	1	6.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL232656	BX 471 FREE BASE	Kd	=	200.0	nM	6.70