Assay Detail
Functional
CHEMBL2184949
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Antimalarial activity against Plasmodium falciparum KT3 gametocytes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Effects of antimalarial molecules on the gametocyte stage of Plasmodium falciparum: the debate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.53 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL35228 | PYRONARIDINE | 3.0 | 1 | 7.70 |
| CHEMBL290441 | — | — | 1 | 6.22 |
| CHEMBL506 | PRIMAQUINE | 4.0 | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL35228 | PYRONARIDINE | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL290441 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL506 | PRIMAQUINE | IC50 | = | 2100.0 | nM | 5.68 |