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Assay Detail

CHEMBL2185178

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Functional
Agonist activity at mGLUR2 expressed in CHO cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Metabotropic glutamate receptor 2 (CHEMBL5137)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Radiosynthesis of PET radiotracer as a prodrug for imaging group II metabotropic glutamate receptors in vivo.
Wang JQ, Zhang Z, Kuruppu D, Brownell AL.
Bioorg Med Chem Lett (2012) 22 : 1958 -1962
PubMed 22318160 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.24 9.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL121053 1 9.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL121053 EC50 = 0.57 nM 9.24