Assay Detail
Functional
CHEMBL2186330
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Cytotoxicity against human M059J cells incubated for 4 days
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | M059J |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The design and identification of brain penetrant inhibitors of phosphoinositide 3-kinase α.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.36 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2178608 | — | — | 1 | 6.48 |
| CHEMBL2178606 | — | — | 1 | 6.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2178608 | — | EC50 | = | 330.0 | nM | 6.48 |
| CHEMBL2178606 | — | EC50 | = | 590.0 | nM | 6.23 |