Assay Detail
Functional
CHEMBL2186980
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Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Down-regulation of the human VEGF gene expression by perylene monoimide derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.89 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2181586 | — | — | 1 | 5.50 |
| CHEMBL2181585 | — | — | 1 | 5.40 |
| CHEMBL65606 | TMPYP4 | — | 1 | 4.37 |
| CHEMBL359594 | — | — | 1 | 4.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2181586 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL2181585 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL65606 | TMPYP4 | IC50 | = | 43100.0 | nM | 4.37 |
| CHEMBL359594 | — | IC50 | = | 52400.0 | nM | 4.28 |