Assay Detail
Binding
CHEMBL2188406
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Binding affinity to NMDAR in Sprague-Dawley rat cerebral cortex homogenates
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Cerebral cortex |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 8.40 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL344151 | DIZOCILPINE MALEATE | -1.0 | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL344151 | DIZOCILPINE MALEATE | Kd | = | 4.0 | nM | 8.40 |