Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL2189053

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of vascular endothelial growth factor receptor 2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Vascular endothelial growth factor receptor 2 (CHEMBL279)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Rational design of highly selective spleen tyrosine kinase inhibitors.
Lucas MC, Goldstein DM, Hermann JC, Kuglstatter A, Liu W, Luk KC, Padilla F, Slade M, Villaseñor AG, Wanner J, Xie W, Zhang X, Liao C.
J Med Chem (2012) 55 : 10414 -10423
PubMed 23151054 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3989516 FOSTAMATINIB DISODIUM 4.0 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3989516 FOSTAMATINIB DISODIUM Kd = 70.0 nM 7.16