Assay Detail
Binding
CHEMBL2208526
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Inhibition of GGTase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.64 | 8.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL159171 | — | — | 1 | 8.77 |
| CHEMBL52073 | — | — | 1 | 6.52 |
| CHEMBL298895 | — | — | 1 | 6.50 |
| CHEMBL526466 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL159171 | — | IC50 | = | 1.7 | nM | 8.77 |
| CHEMBL52073 | — | IC50 | = | 301.0 | nM | 6.52 |
| CHEMBL298895 | — | IC50 | = | 313.0 | nM | 6.50 |
| CHEMBL526466 | — | IC50 | = | 18000.0 | nM | 4.75 |