Assay Detail
Binding
CHEMBL2208531
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Inhibition of CDK1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.90 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL215803 | — | — | 1 | 9.00 |
| CHEMBL1235529 | — | — | 1 | 7.70 |
| CHEMBL2203628 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL215803 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL1235529 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL2203628 | — | IC50 | = | 100.0 | nM | 7.00 |